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mRNA-1273 from Moderna. COVID-19 vaccines

09/02/2021 Epidemiology

General data.

  • Name: mRNA-1273
  • Manufacturer Laboratory: ModernaTX, Inc.
  • Type: mRNA * To learn more about the type of vaccines, check our blog “And so, the war has begun. COVID-19 vaccines”.
  • Dosage: 2 doses with a difference in the time of application of 21 days.
  • Ingredients: messenger ribonucleic acid (mRNA), lipids (SM-102, polyethylene glycol [PEG] 2000 dimyristoyl glycerol [DMG], cholesterol, and 1,2-distearoyl-sn-glycero-3-phosphocholine [DSPC]), tromethamine, tromethamine hydrochloride, acetic acid, sodium acetate, and sucrose.
  • Injection site: Intramuscular in the arm.
  • Recommended age: 18 years old and up.
  • It is not recommended to apply if:
    1. You have had severe allergic reactions to ingredients in the vaccine.
    2. Reacted severely after receiving the first dose of the vaccine, in which case you should not go to the second dose.
    3. Please consider in the two previous cases, allergic reactions to polyethylene glycol (PEG) and polysorbate. Polysorbate is an ingredient that is not included in any of the COVID-19 mRNA vaccines but is closely related to PEG, which is included in vaccines. People who are allergic to PEG or polysorbate should not receive the mRNA vaccine against COVID-19.


  • Immediate Allergic Reactions:

In the injection arm:

  • Pain
  • Swelling
  • Sensitivity
  • Swollen lymph nodes (neck)
  • Hardness
  • Redness

In the body in general:

  • Shaking chills
  • Headache
  • Fatigue
  • Joints pain
  • Muscle pain
  • Nausea
  • Vomiting
  • Fever

In the injection arm:

  • Clean, cold cloths.
  • Moving the arm

In the body in general:

  • Drink lots of liquids.
  • Consult your doctor to take doses of ibuprofen or paracetamol.
  • Special considerations: Check with your doctor before applying the vaccine if you meet any of the following points:
    1. You have allergies, specify which ones.
    2. Have fever.
    3. You have a blood disorder (such as Hemophilia) or if you are taking anticoagulants.
    4. You have a condition that compromises your immune system (eg Lupus) or you take medications that affect your immune system.
    5. You are pregnant or plan to become pregnant.
    6. You are breastfeeding.
    7. You were inoculated with another COVID-19 vaccine.
  • Safety
    1. This vaccine does not yet have the official application permits from the FDA (Food and Drug Administration), however, it does have a special emergency authorization derived from the pandemic, granted by the same agency.
    2. Some of the symptoms of possible serious reactions from the vaccine include:
    3. Shortness of breath.
    4. Swelling in the face and throat.
    5. Heart rate.
    6. Dizziness and Decay.
    7. Skin rash all over the body.
  • Effectiveness: In clinical trials, it recorded a 94.1% efficacy for the prevention of COVID-19 cases, laboratory data from people with no evidence of previous infections.








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